Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

The modified base 5-methylcytosine (m(5)C) is well studied in DNA, but investigations of its prevalence in cellular RNA have been largely confined to tRNA and rRNA. In animals, the two m(5)C methyltransferases NSUN2 and TRDMT1 are known to modify specific tRNAs and have roles in the control of cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Squires, Jeffrey E., Patel, Hardip R., Nousch, Marco, Sibbritt, Tennille, Humphreys, David T., Parker, Brian J., Suter, Catherine M., Preiss, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367185/
https://ncbi.nlm.nih.gov/pubmed/22344696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks144
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