Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

The modified base 5-methylcytosine (m(5)C) is well studied in DNA, but investigations of its prevalence in cellular RNA have been largely confined to tRNA and rRNA. In animals, the two m(5)C methyltransferases NSUN2 and TRDMT1 are known to modify specific tRNAs and have roles in the control of cell...

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Detalhes bibliográficos
Main Authors: Squires, Jeffrey E., Patel, Hardip R., Nousch, Marco, Sibbritt, Tennille, Humphreys, David T., Parker, Brian J., Suter, Catherine M., Preiss, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367185/
https://ncbi.nlm.nih.gov/pubmed/22344696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks144
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