The Greater Sensitivity of Elderly APOE ε4 Carriers to Anticholinergic Medications Is Independent of Cerebrovascular Disease Risk

BACKGROUND: Recent studies found use of anticholinergic medications to be associated with greater performance decrements in older persons who carry an ε4 allele of the apolipoprotein E (APOE) gene than in those carrying only ε2 or ε3 alleles. OBJECTIVES: The present study examined whether the appare...

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Hauptverfasser: Nebes, Robert D., Pollock, Bruce G., Perera, Subashan, Halligan, Edythe M., Saxton, Judith A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367111/
https://ncbi.nlm.nih.gov/pubmed/22534472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjopharm.2012.03.003
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