Binding of Hepatitis A Virus to its Cellular Receptor 1 Inhibits T-Regulatory Cell Functions in Humans

BACKGROUND & AIMS: CD4+ T regulatory (Treg) cells suppress immune responses and control self-tolerance and immunity to pathogens, cancer, and alloantigens. Most pathogens activate Treg cells to minimize immune-mediated tissue damage and prevent clearance, which promotes chronic infections. Howev...

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Detalhes bibliográficos
Main Authors: Manangeeswaran, Mohanraj, Jacques, Jérôme, Tami, Cecilia, Konduru, Krishnamurthy, Amharref, Nadia, Perrella, Oreste, Casasnovas, Jose M., Umetsu, Dale T., DeKruyff, Rosemarie H., Freeman, Gordon J., Perrella, Alessandro, Kaplan, Gerardo G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367104/
https://ncbi.nlm.nih.gov/pubmed/22430395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.02.039
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