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CLONAL EVOLUTION IN CANCER
Cancers evolve by a reiterative process of clonal expansion, genetic diversification and clonal selection within the adaptive landscapes of tissue ecosystems. The dynamics are complex with highly variable patterns of genetic diversity and resultant clonal architecture. Therapeutic intervention may d...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367003/ https://ncbi.nlm.nih.gov/pubmed/22258609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10762 |
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