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Early Dengue Virus Protein Synthesis Induces Extensive Rearrangement of the Endoplasmic Reticulum Independent of the UPR and SREBP-2 Pathway

The rearrangement of intracellular membranes has been long reported to be a common feature in diseased cells. In this study, we used dengue virus (DENV) to study the role of the unfolded protein response (UPR) and sterol-regulatory-element-binding-protein-2 (SREBP-2) pathway in the rearrangement and...

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Detalhes bibliográficos
Main Authors: Peña, José, Harris, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366941/
https://ncbi.nlm.nih.gov/pubmed/22675522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038202
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