Lin-28 Homologue A (LIN28A) Promotes Cell Cycle Progression via Regulation of Cyclin-dependent Kinase 2 (CDK2), Cyclin D1 (CCND1), and Cell Division Cycle 25 Homolog A (CDC25A) Expression in Cancer

The RNA-binding protein LIN28A regulates the translation and stability of a large number of mRNAs as well as the biogenesis of certain miRNAs in embryonic stem cells and developing tissues. Increasing evidence indicates that LIN28A functions as an oncogene promoting cancer cell growth. However, litt...

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Bibliografiske detaljer
Main Authors: Li, Ning, Zhong, Xiaomin, Lin, Xiaojuan, Guo, Jinyi, Zou, Lian, Tanyi, Janos L., Shao, Zhongjun, Liang, Shun, Wang, Li-Ping, Hwang, Wei-Ting, Katsaros, Dionyssios, Montone, Kathleen, Zhao, Xia, Zhang, Lin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366838/
https://ncbi.nlm.nih.gov/pubmed/22467868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.321158
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