Lin-28 Homologue A (LIN28A) Promotes Cell Cycle Progression via Regulation of Cyclin-dependent Kinase 2 (CDK2), Cyclin D1 (CCND1), and Cell Division Cycle 25 Homolog A (CDC25A) Expression in Cancer

The RNA-binding protein LIN28A regulates the translation and stability of a large number of mRNAs as well as the biogenesis of certain miRNAs in embryonic stem cells and developing tissues. Increasing evidence indicates that LIN28A functions as an oncogene promoting cancer cell growth. However, litt...

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Autors principals: Li, Ning, Zhong, Xiaomin, Lin, Xiaojuan, Guo, Jinyi, Zou, Lian, Tanyi, Janos L., Shao, Zhongjun, Liang, Shun, Wang, Li-Ping, Hwang, Wei-Ting, Katsaros, Dionyssios, Montone, Kathleen, Zhao, Xia, Zhang, Lin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366838/
https://ncbi.nlm.nih.gov/pubmed/22467868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.321158
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