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Structural Snapshots of Yeast Alkyl Hydroperoxide Reductase Ahp1 Peroxiredoxin Reveal a Novel Two-cysteine Mechanism of Electron Transfer to Eliminate Reactive Oxygen Species

Peroxiredoxins (Prxs) are thiol-specific antioxidant proteins that protect cells against reactive oxygen species and are involved in cellular signaling pathways. Alkyl hydroperoxide reductase Ahp1 belongs to the Prx5 subfamily and is a two-cysteine (2-Cys) Prx that forms an intermolecular disulfide...

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Detalhes bibliográficos
Main Authors: Lian, Fu-Ming, Yu, Jiang, Ma, Xiao-Xiao, Yu, Xiao-Jie, Chen, Yuxing, Zhou, Cong-Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366830/
https://ncbi.nlm.nih.gov/pubmed/22474296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.357368
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