GTP-binding Protein-like Domain of AGAP1 Is Protein Binding Site That Allosterically Regulates ArfGAP Protein Catalytic Activity

AGAPs are a subtype of Arf GTPase-activating proteins (GAPs) with 11 members in humans. In addition to the Arf GAP domain, the proteins contain a G-protein-like domain (GLD) with homology to Ras superfamily proteins and a PH domain. AGAPs bind to clathrin adaptors, function in post Golgi membrane tr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Luo, Ruibai, Akpan, Itoro O., Hayashi, Ryo, Sramko, Marek, Barr, Valarie, Shiba, Yoko, Randazzo, Paul A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Enzymology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366823/
https://ncbi.nlm.nih.gov/pubmed/22453919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334458
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