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P2X7 Receptor-mediated Scavenger Activity of Mononuclear Phagocytes toward Non-opsonized Particles and Apoptotic Cells Is Inhibited by Serum Glycoproteins but Remains Active in Cerebrospinal Fluid

Rapid phagocytosis of non-opsonized particles including apoptotic cells is an important process that involves direct recognition of the target by multiple scavenger receptors including P2X7 on the phagocyte surface. Using a real-time phagocytosis assay, we studied the effect of serum proteins on thi...

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Detalhes bibliográficos
Main Authors: Gu, Ben J., Duce, James A., Valova, Valentina A., Wong, Bruce, Bush, Ashley I., Petrou, Steven, Wiley, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366774/
https://ncbi.nlm.nih.gov/pubmed/22461619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340885
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