Botulinum Neurotoxin Detection and Differentiation by Mass Spectrometry

Botulinum neurotoxins (BoNTs) are proteases that cleave specific cellular proteins essential for neurotransmitter release. Seven BoNT serotypes (A–G) exist; 4 usually cause human botulism (A, B, E, and F). We developed a rapid, mass spectrometry–based method (Endopep-MS) to detect and differentiate...

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Bibliografiske detaljer
Main Authors: Barr, John R., Moura, Hercules, Boyer, Anne E., Woolfitt, Adrian R., Kalb, Suzanne R., Pavlopoulos, Antonis, McWilliams, Lisa G., Schmidt, Jurgen G., Martinez, Rodolfo A., Ashley, David L.
Format: Artigo
Sprog:Inglês
Udgivet: Centers for Disease Control and Prevention 2005
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366733/
https://ncbi.nlm.nih.gov/pubmed/16318699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1110.041279
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