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Enhancement of fludarabine sensitivity by all-trans-retinoic acid in chronic lymphocytic leukemia cells

BACKGROUND: A subset of patients with fludarabine-resistant chronic lymphocytic leukemia has previously been shown to express elevated intracellular levels of the concentrative high-affinity fludarabine transporter hCNT3, without any detectable related activity. We have recently shown that all-trans...

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Autors principals: Fernández-Calotti, Paula X., Lopez-Guerra, Mónica, Colomer, Dolors, Pastor-Anglada, Marçal
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366664/
https://ncbi.nlm.nih.gov/pubmed/22180426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.051557
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