Fc gamma receptor 3a genotype predicts overall survival in follicular lymphoma patients treated on SWOG trials with combined monoclonal antibody plus chemotherapy but not chemotherapy alone

BACKGROUND: Fc gamma receptor polymorphisms were linked to outcome in follicular lymphoma patients treated with single-agent rituximab, an anti-CD20 monoclonal antibody. In particular, 158F/F genotype of Fc gamma receptor 3A and 131R/R genotype of Fc gamma receptor 2A correlated with worse outcome c...

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Detalhes bibliográficos
Main Authors: Persky, Daniel O., Dornan, David, Goldman, Bryan H., Braziel, Rita M., Fisher, Richard I., LeBlanc, Michael, Maloney, David G., Press, Oliver W., Miller, Thomas P., Rimsza, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366663/
https://ncbi.nlm.nih.gov/pubmed/22271896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.050419
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