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Propylene Glycol produces excessive apoptosis in the developing mouse brain, alone and in combination with Phenobarbital

Propylene Glycol (PG) is a common solvent used in medical preparations. It is “generally recognized as safe” at regulated concentrations, however its apoptotic potential is unknown. C57BL/6 mice (P4–30) were exposed to PG to examine whether PG could produce apoptosis in the developing CNS. PG trigge...

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Detalhes bibliográficos
Main Authors: LAU, KAREN, SWINEY, BRANT S., REEVES, NICK, NOGUCHI, KEVIN K., FARBER, NURI B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366500/
https://ncbi.nlm.nih.gov/pubmed/22289851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2011.12
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