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All in the Family: How the APPs Regulate Neurogenesis

Recent intriguing evidence suggests that metabolites of amyloid precursor protein (APP), mutated in familial forms of Alzheimer’s disease (AD), play critical roles in developmental and postnatal neurogenesis. Of note is soluble APPα (sAPPα) that regulates neural progenitor cell proliferation. The AP...

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Autors principals: Lazarov, Orly, Demars, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366480/
https://ncbi.nlm.nih.gov/pubmed/22675290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2012.00081
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