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All in the Family: How the APPs Regulate Neurogenesis

Recent intriguing evidence suggests that metabolites of amyloid precursor protein (APP), mutated in familial forms of Alzheimer’s disease (AD), play critical roles in developmental and postnatal neurogenesis. Of note is soluble APPα (sAPPα) that regulates neural progenitor cell proliferation. The AP...

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Detalhes bibliográficos
Main Authors: Lazarov, Orly, Demars, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366480/
https://ncbi.nlm.nih.gov/pubmed/22675290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2012.00081
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