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Modulation of microRNA Activity by Semi-microRNAs

The ribonuclease Dicer plays a central role in the microRNA pathway by catalyzing the formation of 19–24-nucleotide (nt) long microRNAs. Subsequently incorporated into Argonaute 2 (Ago2) effector complexes, microRNAs are known to regulate messenger RNA (mRNA) translation. Whether shorter RNA species...

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Détails bibliographiques
Auteurs principaux: Plante, Isabelle, Plé, Hélène, Landry, Patricia, Gunaratne, Preethi H., Provost, Patrick
Format: Artigo
Langue:Inglês
Publié: Frontiers Research Foundation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366366/
https://ncbi.nlm.nih.gov/pubmed/22675332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00099
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