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CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers

Although imatinib mesylate has been a major breakthrough in the treatment of advanced GIST, complete responses are rare and most patients eventually develop resistance to the drug. Thus the possibility of an imatinib-insensitive cell subpopulation within GIST tumors, harboring stem cell characterist...

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Detalhes bibliográficos
Main Authors: Chen, Junwei, Guo, Tianhua, Zhang, Lei, Qin, Li-Xuan, Singer, Samuel, Maki, Robert G., Taguchi, Takahiro, DeMatteo, Ronald, Besmer, Peter, Antonescu, Cristina R
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366284/
https://ncbi.nlm.nih.gov/pubmed/22076958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20942
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