Expression of GA733-Fc Fusion Protein as a Vaccine Candidate for Colorectal Cancer in Transgenic Plants

The tumor-associated antigen GA733 is a cell-surface glycoprotein highly expressed in colorectal carcinomas. In this study, 3 recombinant genes were constructed as follows: GA733 tagged to the ER retention sequence KDEL (GA733K), GA733 fused to the immunoglobulin Fc fragment (GA733-Fc), and GA733-Fc...

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Autori principali: Lu, Zhe, Lee, Kyung-Jin, Shao, Yingxue, Lee, Jeong-Hwan, So, Yangkang, Choo, Young-Kug, Oh, Doo-Byoung, Hwang, Kyung-A, Oh, Seung Han, Han, Yeon Soo, Ko, Kisung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366255/
https://ncbi.nlm.nih.gov/pubmed/22675251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/364240
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