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CCR5 Promoter Polymorphisms in a Kenyan Perinatal Human Immunodeficiency Virus Type 1 Cohort: Association with Increased 2-Year Maternal Mortality

The CCR5 chemokine receptor acts as a coreceptor with CD4 to permit infection by primary macrophage-tropic human immunodeficiency virus type 1 (HIV-1) strains. The CCR5Δ32 mutation, which is associated with resistance to infection in homozygous individuals and delayed disease progression in heterozy...

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Detalhes bibliográficos
Main Authors: John, Grace C., Bird, Thomas, Overbaugh, Julie, Nduati, Ruth, Mbori-Ngacha, Dorothy, Rostron, Tim, Dong, Tao, Kostrikis, Leondios, Richardson, Barbra, Rowland-Jones, Sarah L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366112/
https://ncbi.nlm.nih.gov/pubmed/11398114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/321006
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