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Knowledge-based Potential for Positioning Membrane-Associated Structures and Assessing Residue Specific Energetic Contributions

The complex hydrophobic and hydrophilic milieus of membrane-associated proteins pose experimental and theoretical challenges to their understanding. Here we produce a non-redundant database to compute knowledge-based asymmetric cross-membrane potentials from the per-residue distributions of C(β), C(...

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Autori principali: Schramm, Chaim A., Hannigan, Brett T., Donald, Jason E., Keasar, Chen, Saven, Jeffrey G., DeGrado, William F., Samish, Ilan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366090/
https://ncbi.nlm.nih.gov/pubmed/22579257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.03.016
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