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In vitro differentiation of mouse embryonic stem cells into inner ear hair cell-like cells using stromal cell conditioned medium

Hearing loss is mainly caused by loss of sensory hair cells (HCs) in the organ of Corti or cochlea. Although embryonic stem (ES) cells are a promising source for cell therapy, little is known about the efficient generation of HC-like cells from ES cells. In the present study, we developed a single-m...

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Detalhes bibliográficos
Main Authors: Ouji, Y, Ishizaka, S, Nakamura-Uchiyama, F, Yoshikawa, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366087/
https://ncbi.nlm.nih.gov/pubmed/22622133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.56
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