p57(KIP2) control of actin cytoskeleton dynamics is responsible for its mitochondrial pro-apoptotic effect

p57 (Kip2, cyclin-dependent kinase inhibitor 1C), often found downregulated in cancer, is reported to hold tumor suppressor properties. Originally described as a cyclin-dependent kinase (cdk) inhibitor, p57(KIP2) has since been shown to influence other cellular processes, beyond cell cycle regulatio...

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Bibliografiske detaljer
Main Authors: Kavanagh, E, Vlachos, P, Emourgeon, V, Rodhe, J, Joseph, B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366085/
https://ncbi.nlm.nih.gov/pubmed/22592318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.51
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