Is ethnicity associated with morphine's side effects in children? morphine pharmacokinetics, analgesic response and side effects in children having tonsillectomy

OBJECTIVES/AIMS: To examine whether morphine pharmacokinetics (PK) and/or genetic polymorphisms in opioid-related genes, underlie differences in analgesic response and side effects to morphine in Latino (L) vs non-Latino Caucasian (NL) children. BACKGROUND: Morphine has high interindividual variabil...

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Bibliographic Details
Main Authors: Jimenez, Nathalia, Anderson, Gail D., Shen, Danny D., Nielsen, Susan Searles, Farin, Federico M., Seidel, Kristy, Lynn, Anne M.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366036/
https://ncbi.nlm.nih.gov/pubmed/22486937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9592.2012.03844.x
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