Overexpression of Hyaluronan-binding Protein 1 (HABP1/p32/gC1qR) in HepG2 Cells Leads to Increased Hyaluronan Synthesis and Cell Proliferation by Up-regulation of Cyclin D1 in AKT-dependent Pathway

Overexpression of the mature form of hyaluronan-binding protein 1 (HABP1/gC1qR/p32), a ubiquitous multifunctional protein involved in cellular signaling, in normal murine fibroblast cells leads to enhanced generation of reactive oxygen species (ROS), mitochondrial dysfunction, and ultimately apoptos...

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Detalhes bibliográficos
Main Authors: Kaul, Rachna, Saha, Paramita, Saradhi, Mallampati, Prasad, Ramachandra L. A., Chatterjee, Soumya, Ghosh, Ilora, Tyagi, Rakesh K., Datta, Kasturi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366008/
https://ncbi.nlm.nih.gov/pubmed/22451658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266270
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