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Essential Functions of C Terminus of Drosophila Topoisomerase IIIα in Double Holliday Junction Dissolution

Topoisomerase IIIα (Top3α) is an essential component of the double Holliday junction (dHJ) dissolvasome complex in metazoans, along with Blm and Rmi1/2. This important anti-recombinogenic function cannot be performed by Top3β, the other type IA topoisomerase present in metazoans. The two share a cat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Stefanie Hartman, Wu, Chung-Hsuan, Plank, Jody L., Hsieh, Tao-shih
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365971/
https://ncbi.nlm.nih.gov/pubmed/22511792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363044
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