MicroRNAs Are Essential for Stretch-induced Vascular Smooth Muscle Contractile Differentiation via MicroRNA (miR)-145-dependent Expression of L-type Calcium Channels

Stretch of the vascular wall is an important stimulus to maintain smooth muscle contractile differentiation that is known to depend on L-type calcium influx, Rho-activation, and actin polymerization. The role of microRNAs in this response was investigated using tamoxifen-inducible and smooth muscle-...

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Main Authors: Turczyńska, Karolina M., Sadegh, Mardjaneh Karbalaei, Hellstrand, Per, Swärd, Karl, Albinsson, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365952/
https://ncbi.nlm.nih.gov/pubmed/22474293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341073
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