Palytoxin and an Ostreopsis Toxin Extract Increase the Levels of mRNAs Encoding Inflammation-Related Proteins in Human Macrophages via p38 MAPK and NF-κB

BACKGROUND: Palytoxin and, likely, its analogues produced by the dinoflagellate genus Ostreopsis, represent a class of non-proteinaceous compounds displaying high toxicity in animals. Owing to the wide distribution and the poisonous effects of these toxins in humans, their chemistry and mechanism of...

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Detalhes bibliográficos
Main Authors: Crinelli, Rita, Carloni, Elisa, Giacomini, Elisa, Penna, Antonella, Dominici, Sabrina, Battocchi, Cecilia, Ciminiello, Patrizia, Dell'Aversano, Carmela, Fattorusso, Ernesto, Forino, Martino, Tartaglione, Luciana, Magnani, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365899/
https://ncbi.nlm.nih.gov/pubmed/22675515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038139
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