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Circadian Autodephosphorylation of Cyanobacterial Clock Protein KaiC Occurs via Formation of ATP as Intermediate

The cyanobacterial circadian oscillator can be reconstituted in vitro; mixing three clock proteins (KaiA, KaiB, and KaiC) with ATP results in an oscillation of KaiC phosphorylation with a periodicity of ∼24 h. The hexameric ATPase KaiC hydrolyzes ATP bound at subunit interfaces. KaiC also exhibits a...

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Detalhes bibliográficos
Main Authors: Nishiwaki, Taeko, Kondo, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365771/
https://ncbi.nlm.nih.gov/pubmed/22493509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.350660
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