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Assessing Actual Contribution of IF1, Inhibitor of Mitochondrial F(o)F(1), to ATP Homeostasis, Cell Growth, Mitochondrial Morphology, and Cell Viability
F(o)F(1)-ATP synthase (F(o)F(1)) synthesizes ATP in mitochondria coupled with proton flow driven by the proton motive force (pmf) across membranes. It has been known that isolated IF1, an evolutionarily well conserved mitochondrial protein, can inhibit the ATP hydrolysis activity of F(o)F(1). Here,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365700/ https://ncbi.nlm.nih.gov/pubmed/22493494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.345793 |
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