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Amyloid β (Aβ) Peptide Directly Activates Amylin-3 Receptor Subtype by Triggering Multiple Intracellular Signaling Pathways

The two age-prevalent diseases Alzheimer disease and type 2 diabetes mellitus share many common features including the deposition of amyloidogenic proteins, amyloid β protein (Aβ) and amylin (islet amyloid polypeptide), respectively. Recent evidence suggests that both Aβ and amylin may express their...

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Detalhes bibliográficos
Main Authors: Fu, Wen, Ruangkittisakul, Araya, MacTavish, David, Shi, Jenny Y., Ballanyi, Klaus, Jhamandas, Jack H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365692/
https://ncbi.nlm.nih.gov/pubmed/22500019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.331181
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