RNA encapsidation by SV40-derived nanoparticles follows a rapid two-state mechanism

Remarkably, uniform virus-like particles self-assemble in a process that appears to follow a rapid kinetic mechanism. The mechanisms by which spherical viruses assemble from hundreds of capsid proteins around nucleic acid, however, are yet unresolved. Using Time-Resolved Small-Angle X-ray Scattering...

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Bibliographic Details
Main Authors: Kler, Stanislav, Asor, Roi, Li, Chenglei, Ginsburg, Avi, Harries, Daniel, Oppenheim, Ariella, Zlotnick, Adam, Raviv, Uri
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365646/
https://ncbi.nlm.nih.gov/pubmed/22329660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2110703
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