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Characterization of repetitive sequence families in mouse heart small polydisperse circular DNAs: age-related studies.
Using alkaline denaturation-renaturation, exonuclease III digestion and density gradient centrifugations, we have isolated covalently closed circular DNA (cccDNA) molecules from 1-, 8-, 16-, and 24-month C57BL/6 mouse heart tissues. Electron microscopic analyses demonstrated that all these preparati...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1988
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC336563/ https://ncbi.nlm.nih.gov/pubmed/3375074 |
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