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Immortal time bias in critical care research: application of time-varying Cox regression for observational cohort studies
OBJECTIVES: To determine the magnitude of bias when using time-fixed methodology to analyze the effect of a time-varying exposure incurred in the ICU on ICU length of stay. DESIGN: Prospective cohort study (Part 1) and Monte Carlo stimulation study (Part 2) SETTING: Medical and coronary intensive ca...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365557/ https://ncbi.nlm.nih.gov/pubmed/19770737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181b7fbbb |
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