The Formation and Stability of DC-SIGN Microdomains Require its Extracellular Moiety

DC-SIGN (Dendritic cell-specific ICAM-3-grabbing non-integrin) is a Ca(2+)-dependent transmembrane lectin that binds a large variety of pathogens and facilitates their uptake for subsequent antigen presentation. This receptor is present in cell surface microdomains, but factors involved in microdoma...

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Bibliographic Details
Main Authors: Liu, Ping, Wang, Xiang, Itano, Michelle S., Neumann, Aaron K., Jacobson, Ken, Thompson, Nancy L.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365552/
https://ncbi.nlm.nih.gov/pubmed/22292921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2012.01337.x
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