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Functional analysis of interaction sites on the N-terminal domain of clathrin heavy chain

In clathrin-mediated membrane traffic, clathrin does not bind directly to cargo and instead binds to adaptors that mediate this function. For endocytosis, the main adaptor is the AP-2 complex but it is uncertain how clathrin contacts AP-2. Here, we tested in human cells the importance of the three b...

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Autors principals: Willox, Anna K., Royle, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365446/
https://ncbi.nlm.nih.gov/pubmed/21939487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01289.x
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