Sumoylation regulates Kap114-mediated nuclear transport

The nuclear import receptor Kap114 carries transcription factors and other cargos across nuclear pores into the nucleus. Here we show that yeast Kap114 is modified by SUMO (small ubiquitin-related modifier) and that sumoylation is required for Kap114-mediated nuclear import. Among the four known SUM...

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Bibliografiske detaljer
Main Authors: Rothenbusch, Ute, Sawatzki, Marc, Chang, Yiming, Caesar, Stefanie, Schlenstedt, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365415/
https://ncbi.nlm.nih.gov/pubmed/22562154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.102
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