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Severe acute intermittent hypoxia elicits phrenic long-term facilitation by a novel adenosine-dependent mechanism
Acute intermittent hypoxia [AIH; 3, 5-min episodes; 35–45 mmHg arterial Po(2) (Pa(O(2)))] elicits serotonin-dependent phrenic long-term facilitation (pLTF), a form of phrenic motor facilitation (pMF) initiated by G(q) protein-coupled metabotropic 5-HT(2) receptors. An alternate pathway to pMF is ind...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365407/ https://ncbi.nlm.nih.gov/pubmed/22403346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00060.2012 |
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