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Insufficient DNA methylation affects healthy aging and promotes age-related health problems

DNA methylation plays an integral role in development and aging through epigenetic regulation of genome function. DNA methyltransferase 1 (Dnmt1) is the most prevalent DNA methyltransferase that maintains genomic methylation stability. To further elucidate the function of Dnmt1 in aging and age-rela...

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Detalhes bibliográficos
Main Authors: Liu, Liang, van Groen, Thomas, Kadish, Inga, Li, Yuanyuan, Wang, Deli, James, Smitha R., Karpf, Adam R., Tollefsbol, Trygve O.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365396/
https://ncbi.nlm.nih.gov/pubmed/22704347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13148-011-0042-6
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