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Gravity-oriented microfluidic device for uniform and massive cell spheroid formation

We propose a simple method for forming massive and uniform three-dimensional (3-D) cell spheroids in a multi-level structured microfluidic device by gravitational force. The concept of orienting the device vertically has allowed spheroid formation, long-term perfusion, and retrieval of the cultured...

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Hlavní autoři: Lee, Kangsun, Kim, Choong, Young Yang, Jae, Lee, Hun, Ahn, Byungwook, Xu, Linfeng, Yoon Kang, Ji, Oh, Kwang W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Institute of Physics 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365350/
https://ncbi.nlm.nih.gov/pubmed/22662098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3687409
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