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Absence of Ca(2+)-stimulated adenylyl cyclases leads to reduced synaptic plasticity and impaired experience-dependent fear memory
Ca(2+)-stimulated adenylyl cyclase (AC) 1 and 8 are two genes that have been shown to play critical roles in fear memory. AC1 and AC8 couple neuronal activity and intracellular Ca(2+) increases to the production of cyclic adenosine monophosphate and are localized synaptically, suggesting that Ca(2+)...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365269/ https://ncbi.nlm.nih.gov/pubmed/22832970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.50 |
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