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Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer’s disease
Alzheimer’s disease (AD) is characterized by a progressive dysfunction of central neurons. Recent experimental evidence indicates that in the cortex, in addition to the silencing of a fraction of neurons, other neurons are hyperactive in amyloid-β (Aβ) plaque-enriched regions. However, it has remain...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365221/ https://ncbi.nlm.nih.gov/pubmed/22592800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206171109 |
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