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Regulatory changes contribute to the adaptive enhancement of thermogenic capacity in high-altitude deer mice

In response to hypoxic stress, many animals compensate for a reduced cellular O(2) supply by suppressing total metabolism, thereby reducing O(2) demand. For small endotherms that are native to high-altitude environments, this is not always a viable strategy, as the capacity for sustained aerobic the...

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Main Authors: Cheviron, Zachary A., Bachman, Gwendolyn C., Connaty, Alex D., McClelland, Grant B., Storz, Jay F.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365185/
https://ncbi.nlm.nih.gov/pubmed/22586089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120523109
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