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Acrolein Induces Endoplasmic Reticulum Stress and Causes Airspace Enlargement

BACKGROUND: Given the relative abundance and toxic potential of acrolein in inhaled cigarette smoke, it is surprising how little is known about the pulmonary and systemic effects of acrolein. Here we test the hypothesis whether systemic administration of acrolein could cause endoplasmic reticulum (E...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kitaguchi, Yoshiaki, Taraseviciene-Stewart, Laimute, Hanaoka, Masayuki, Natarajan, Ramesh, Kraskauskas, Donatas, Voelkel, Norbert F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364999/
https://ncbi.nlm.nih.gov/pubmed/22675432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038038
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