Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22

A substantial proportion of familial colorectal cancer (CRC) is not a consequence of known susceptibility loci, such as mismatch repair (MMR) genes, supporting the existence of additional loci. To identify novel CRC loci, we conducted a genome-wide linkage scan in 356 white families with no evidence...

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Autores principales: Cicek, Mine S., Cunningham, Julie M., Fridley, Brooke L., Serie, Daniel J., Bamlet, William R., Diergaarde, Brenda, Haile, Robert W., Le Marchand, Loic, Krontiris, Theodore G., Younghusband, H. Banfield, Gallinger, Steven, Newcomb, Polly A., Hopper, John L., Jenkins, Mark A., Casey, Graham, Schumacher, Fredrick, Chen, Zhu, DeRycke, Melissa S., Templeton, Allyson S., Winship, Ingrid, Green, Roger C., Green, Jane S., Macrae, Finlay A., Parry, Susan, Young, Graeme P., Young, Joanne P., Buchanan, Daniel, Thomas, Duncan C., Bishop, D. Timothy, Lindor, Noralane M., Thibodeau, Stephen N., Potter, John D., Goode, Ellen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364975/
https://ncbi.nlm.nih.gov/pubmed/22675446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038175
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