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Physicochemical properties of phosphorothioate oligodeoxynucleotides.
We have recently shown that phosphorothioate (PS) oligodeoxynucleotide (ODN) analogs, unlike their normal congeners, exhibit significant anti-HIV activity (Matsukura et al., (1987) Proc. Natl. Acad. Sci. USA 84, 7706-7710). We now report the syntheses, melting temperatures (Tm), and nuclease suscept...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1988
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336489/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2836790/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.8.3209 |
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