Physicochemical properties of phosphorothioate oligodeoxynucleotides.

We have recently shown that phosphorothioate (PS) oligodeoxynucleotide (ODN) analogs, unlike their normal congeners, exhibit significant anti-HIV activity (Matsukura et al., (1987) Proc. Natl. Acad. Sci. USA 84, 7706-7710). We now report the syntheses, melting temperatures (Tm), and nuclease suscept...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Stein, C A, Subasinghe, C, Shinozuka, K, Cohen, J S
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1988
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336489/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2836790/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.8.3209
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