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Microfluidic endothelial cell culture model to replicate disturbed flow conditions seen in atherosclerosis susceptible regions

Atherosclerotic lesions occur non-randomly at vascular niches in bends and bifurcations where fluid flow can be characterized as “disturbed” (low shear stress with both forward and retrograde flow). Endothelial cells (ECs) at these locations experience significantly lower average shear stress withou...

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Detalhes bibliográficos
Main Authors: Estrada, Rosendo, Giridharan, Guruprasad A., Nguyen, Mai-Dung, Prabhu, Sumanth D., Sethu, Palaniappan
Formato: Artigo
Idioma:Inglês
Publicado em: American Institute of Physics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364817/
https://ncbi.nlm.nih.gov/pubmed/22662029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3608137
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