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Simulation of conformational preconditioning strategies for electrophoretic stretching of DNA in a microcontraction

We have used Brownian dynamics-finite element method to examine two conformational preconditioning approaches for improving DNA stretching in a microcontraction for the purpose of direct gene analysis. The newly proposed “pre-stretching” strategy is found to significantly improve the degree of DNA e...

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Detalhes bibliográficos
Main Authors: Hsieh, Chih-Chen, Lin, Tsung-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: American Institute of Physics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364805/
https://ncbi.nlm.nih.gov/pubmed/22662058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3655565
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