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Simulation of conformational preconditioning strategies for electrophoretic stretching of DNA in a microcontraction
We have used Brownian dynamics-finite element method to examine two conformational preconditioning approaches for improving DNA stretching in a microcontraction for the purpose of direct gene analysis. The newly proposed “pre-stretching” strategy is found to significantly improve the degree of DNA e...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Institute of Physics
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364805/ https://ncbi.nlm.nih.gov/pubmed/22662058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3655565 |
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