Preparation of covalently linked DNA-RNA hybrids and arabinocytidine containing DNA fragments.

It will be demonstrated that 5'-O-DMT-N-acyl-deoxyribonucleosides, 5'-O-Lev-2'-O-MTHP-N-acyl-ribonucleosides and, also, 2'-O-MTHP-N-acyl-ara-cytidine can be coupled, via the hydroxybenzotriazole phosphotriester approach, to afford two types of DNA-RNA hybrids as well as ara-C con...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: de Vroom, E, Roelen, H C, Saris, C P, Budding, T N, van der Marel, G A, van Boom, J H
Format: Artigo
Language:Inglês
Published: Oxford University Press 1988
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2453027/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.7.2987
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