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Physicochemical Properties of Amorphous Roxithromycin Prepared by Quench Cooling of the Melt or Desolvation of a Chloroform Solvate

Roxithromycin is a poorly soluble antibacterial drug. The aim of this study was to prepare and characterize an amorphous form of roxithromycin. The amorphous form was prepared by desolvation of its chloroform solvate, and by quench cooling a melt of the crystalline monohydrated solid. The X-ray powd...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Aucamp, Marique, Liebenberg, Wilna, Strydom, Schalk J., van Tonder, Elsa C., de Villiers, Melgardt M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364397/
https://ncbi.nlm.nih.gov/pubmed/22391887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9766-7
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