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Modulation of Human Mesenchymal Stem Cell Immunogenicity through Forced Expression of Human Cytomegalovirus US Proteins

BACKGROUND: Mesenchymal stem cells (MSC) are promising candidates for cell therapy, as they migrate to areas of injury, differentiate into a broad range of specialized cells, and have immunomodulatory properties. However, MSC are not invisible to the recipient's immune system, and upon in vivo...

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Main Authors: Soland, Melisa A., Bego, Mariana G., Colletti, Evan, Porada, Christopher D., Zanjani, Esmail D., St. Jeor, Stephen, Almeida-Porada, Graça
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364258/
https://ncbi.nlm.nih.gov/pubmed/22666319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036163
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