Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects

CONTEXT: Expression and activity of the main lipogenic enzymes is paradoxically decreased in obesity, but the mechanisms behind these findings are poorly known. Breast Cancer 1 (BrCa1) interacts with acetyl-CoA carboxylase (ACC) reducing the rate of fatty acid biosynthesis. In this study, we aimed t...

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Detalhes bibliográficos
Main Authors: Ortega, Francisco J., Moreno-Navarrete, José M., Mayas, Dolores, García-Santos, Eva, Gómez-Serrano, María, Rodriguez-Hermosa, José I., Ruiz, Bartomeu, Ricart, Wifredo, Tinahones, Francisco J., Frühbeck, Gema, Peral, Belen, Fernández-Real, José M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364252/
https://ncbi.nlm.nih.gov/pubmed/22666314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033233
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